Retinoic acid receptor gamma · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P18911. Use UniProt P18911 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P18911 as the stable identity anchor, then attach disease evidence before program review.
Retinoic acid receptor gamma
Review this target as Retinoic acid receptor gamma, mapped to UniProt P18911. Sequence length is 458 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Retinoic acid receptor gamma as ChEMBL target CHEMBL4177, mapped to UniProt P18911. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Retinoic acid receptor gamma is the right protein anchor across sources, using UniProt P18911 as the stable mapping.
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| Preferred Name | Retinoic acid receptor gamma |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P18911 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinoic acid receptor gamma |
| UniProt Accession | P18911 |
| Component Type | Protein |
| Sequence Length | 458 aa |
Retinoic acid receptor gamma
Review this target as Retinoic acid receptor gamma, mapped to UniProt P18911. Sequence length is 458 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL38 | 9.66 | EC50 | 0.22 | Approved |
| CHEMBL46398 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL4572914 | 8.55 | EC50 | 2.8 | Preclinical |
| CHEMBL38 | 8.4 | IC50 | 4.0 | Approved |
| CHEMBL4442948 | 8.27 | EC50 | 5.4 | Preclinical |
| CHEMBL4531897 | 8.26 | EC50 | 5.5 | Preclinical |
| CHEMBL198997 | 8.24 | EC50 | 5.8 | Preclinical |
| CHEMBL4469143 | 8.19 | EC50 | 6.4 | Preclinical |
| CHEMBL4449668 | 8.14 | EC50 | 7.3 | Preclinical |
| CHEMBL4439399 | 8.12 | EC50 | 7.6 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 11 | 24 | 7.7 |
| single protein format | 4 | 13 | 6.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |