S-adenosylmethionine decarboxylase proenzyme · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-15Protein identity stays anchored to UniProt P17707. Use UniProt P17707 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P17707 as the stable identity anchor, then attach disease evidence before program review.
S-adenosylmethionine decarboxylase proenzyme
Review this target as S-adenosylmethionine decarboxylase proenzyme, mapped to UniProt P17707. Sequence length is 334 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats S-adenosylmethionine decarboxylase proenzyme as ChEMBL target CHEMBL4181, mapped to UniProt P17707. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | S-adenosylmethionine decarboxylase proenzyme |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P17707 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | S-adenosylmethionine decarboxylase proenzyme |
| UniProt Accession | P17707 |
| Component Type | Protein |
| Sequence Length | 334 aa |
S-adenosylmethionine decarboxylase proenzyme
Review this target as S-adenosylmethionine decarboxylase proenzyme, mapped to UniProt P17707. Sequence length is 334 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL517131 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL510356 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL461970 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL461779 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL516811 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL460719 | 7.31 | IC50 | 49.0 | Preclinical |
| CHEMBL461780 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL453372 | 7.07 | IC50 | 86.0 | Preclinical |
| CHEMBL517593 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL462656 | 6.4 | IC50 | 400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 27 | 40 | 5.6 |
| cell-based format | 10 | 1 | 4.4 |
| assay format | 2 | 0 | — |