Proteasome Macropain subunit · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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As of 2026-09-14Protein identity stays anchored to UniProt P22141. Use UniProt P22141 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P22141 as the stable identity anchor, then attach disease evidence before program review.
Proteasome subunit beta type-4
Review this target as Proteasome Macropain subunit, mapped to UniProt P22141. ChEMBL maps the protein component as Proteasome subunit beta type-4. Sequence length is 198 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Proteasome Macropain subunit as ChEMBL target CHEMBL4206, mapped to UniProt P22141. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Proteasome Macropain subunit is the right protein anchor across sources, using UniProt P22141 as the stable mapping.
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| Preferred Name | Proteasome Macropain subunit |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P22141 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proteasome subunit beta type-4 |
| UniProt Accession | P22141 |
| Component Type | Protein |
| Sequence Length | 198 aa |
Proteasome subunit beta type-4
Review this target as Proteasome Macropain subunit, mapped to UniProt P22141. ChEMBL maps the protein component as Proteasome subunit beta type-4. Sequence length is 198 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL209258 | 4.17 | Ki | 68000.0 | Preclinical |
| CHEMBL209196 | 4.11 | Ki | 78000.0 | Preclinical |
| CHEMBL209275 | 4.1 | Ki | 80000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 4 | 4.1 |