Use UniProt O24855 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4211 Target Snapshot
Carbonic anhydrase · SINGLE PROTEIN · Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori)
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As of 2026-09-14Protein identity stays anchored to UniProt O24855. Use UniProt O24855 as the stable identity anchor, then attach disease evidence before program review.
Carbonic anhydrase
Review this target as Carbonic anhydrase, mapped to UniProt O24855. Sequence length is 221 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Carbonic anhydrase as ChEMBL target CHEMBL4211, mapped to UniProt O24855. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Carbonic anhydrase is the right protein anchor across sources, using UniProt O24855 as the stable mapping.
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| Preferred Name | Carbonic anhydrase |
| Target Type | SINGLE PROTEIN |
| Organism | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) |
| UniProt | O24855 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carbonic anhydrase |
| UniProt Accession | O24855 |
| Component Type | Protein |
| Sequence Length | 221 aa |
Carbonic anhydrase
How to read this target
Review this target as Carbonic anhydrase, mapped to UniProt O24855. Sequence length is 221 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL206295 | 7.92 | Ki | 12.0 | Preclinical |
| CHEMBL206657 | 7.89 | Ki | 13.0 | Preclinical |
| CHEMBL20 | 7.7 | Ki | 20.0 | Approved |
| CHEMBL204049 | 7.57 | Ki | 27.0 | Preclinical |
| CHEMBL204954 | 7.51 | Ki | 31.0 | Preclinical |
| CHEMBL266240 | 7.39 | Ki | 41.0 | Preclinical |
| CHEMBL204077 | 7.29 | Ki | 51.0 | Preclinical |
| CHEMBL203498 | 7.22 | Ki | 60.0 | Preclinical |
| CHEMBL381544 | 7.21 | Ki | 62.0 | Preclinical |
| CHEMBL6633 | 7.14 | Ki | 72.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 2 assays, 47 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 47 | 6.6 |