Tegument protein VP16 · SINGLE PROTEIN · Herpes simplex virus (type 1 / strain 17)
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As of 2026-09-14Protein identity stays anchored to UniProt P06492. Use UniProt P06492 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P06492 as the stable identity anchor, then attach disease evidence before program review.
Tegument protein VP16
Review this target as Tegument protein VP16, mapped to UniProt P06492. Sequence length is 490 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tegument protein VP16 as ChEMBL target CHEMBL4218, mapped to UniProt P06492. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tegument protein VP16 |
| Target Type | SINGLE PROTEIN |
| Organism | Herpes simplex virus (type 1 / strain 17) |
| UniProt | P06492 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tegument protein VP16 |
| UniProt Accession | P06492 |
| Component Type | Protein |
| Sequence Length | 490 aa |
Tegument protein VP16
Review this target as Tegument protein VP16, mapped to UniProt P06492. Sequence length is 490 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1276308 | 9.15 | EC50 | 0.7 | Approved |
| CHEMBL363151 | 8.15 | EC50 | 7.0 | Preclinical |
| CHEMBL193836 | 6.56 | EC50 | 272.6 | Preclinical |
| CHEMBL1399772 | 5.5 | IC50 | 3197.0 | Preclinical |
| CHEMBL1413178 | 5.46 | IC50 | 3503.0 | Preclinical |
| CHEMBL1383315 | 5.4 | IC50 | 3976.0 | Preclinical |
| CHEMBL1893675 | 5.39 | IC50 | 4102.0 | Preclinical |
| CHEMBL1373969 | 5.33 | IC50 | 4713.0 | Preclinical |
| CHEMBL1965376 | 5.33 | IC50 | 4648.0 | Preclinical |
| CHEMBL479368 | 5.32 | IC50 | 4771.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 234 | 4.8 |
| assay format | 2 | 2 | 8.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 6.6 |