17-beta-hydroxysteroid dehydrogenase type 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P37058. Use UniProt P37058 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P37058 as the stable identity anchor, then attach disease evidence before program review.
17-beta-hydroxysteroid dehydrogenase type 3
Review this target as 17-beta-hydroxysteroid dehydrogenase type 3, mapped to UniProt P37058. Sequence length is 310 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 17-beta-hydroxysteroid dehydrogenase type 3 as ChEMBL target CHEMBL4234, mapped to UniProt P37058. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 17-beta-hydroxysteroid dehydrogenase type 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P37058 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 17-beta-hydroxysteroid dehydrogenase type 3 |
| UniProt Accession | P37058 |
| Component Type | Protein |
| Sequence Length | 310 aa |
17-beta-hydroxysteroid dehydrogenase type 3
Review this target as 17-beta-hydroxysteroid dehydrogenase type 3, mapped to UniProt P37058. Sequence length is 310 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL206384 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL206432 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL206167 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL204882 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL206405 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL2018254 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL383546 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL589158 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL382563 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL206331 | 8.7 | IC50 | 2.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 43 | 128 | 7.0 |
| single protein format | 15 | 63 | 7.1 |
| microsome format | 3 | 5 | 5.6 |
| tissue-based format | 1 | 1 | 8.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 0 | — |