Inositol polyphosphate-5-phosphatase A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q14642. Use UniProt Q14642 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q14642 as the stable identity anchor, then attach disease evidence before program review.
Inositol polyphosphate-5-phosphatase A
Review this target as Inositol polyphosphate-5-phosphatase A, mapped to UniProt Q14642. Sequence length is 412 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Inositol polyphosphate-5-phosphatase A as ChEMBL target CHEMBL4243, mapped to UniProt Q14642. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Inositol polyphosphate-5-phosphatase A is the right protein anchor across sources, using UniProt Q14642 as the stable mapping.
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| Preferred Name | Inositol polyphosphate-5-phosphatase A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q14642 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Inositol polyphosphate-5-phosphatase A |
| UniProt Accession | Q14642 |
| Component Type | Protein |
| Sequence Length | 412 aa |
Inositol polyphosphate-5-phosphatase A
Review this target as Inositol polyphosphate-5-phosphatase A, mapped to UniProt Q14642. Sequence length is 412 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1161242 | 5.89 | Ki | 1300.0 | Preclinical |
| CHEMBL2092837 | 5.41 | Ki | 3900.0 | Preclinical |
| CHEMBL4538474 | 5.4 | IC50 | 4000.0 | Preclinical |
| CHEMBL1160800 | 4.94 | Ki | 11500.0 | Preclinical |
| CHEMBL4473747 | 4.85 | IC50 | 14000.0 | Preclinical |
| CHEMBL279107 | 4.82 | Ki | 15000.0 | Preclinical |
| CHEMBL4453163 | 4.8 | IC50 | 16000.0 | Preclinical |
| CHEMBL1160797 | 4.78 | Ki | 16500.0 | Preclinical |
| CHEMBL1161466 | 4.58 | Ki | 26000.0 | Preclinical |
| CHEMBL4454154 | 4.11 | IC50 | 78000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 14 | 4.7 |
| single protein format | 2 | 2 | 5.2 |