CG8425-PA [Drosophila melanogaster] · SINGLE PROTEIN · Drosophila melanogaster
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As of 2026-09-13Protein identity stays anchored to UniProt A1ZA98. Use UniProt A1ZA98 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A1ZA98 as the stable identity anchor, then attach disease evidence before program review.
Carboxylic ester hydrolase
Review this target as CG8425-PA [Drosophila melanogaster], mapped to UniProt A1ZA98. ChEMBL maps the protein component as Carboxylic ester hydrolase. Sequence length is 579 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats CG8425-PA [Drosophila melanogaster] as ChEMBL target CHEMBL4265, mapped to UniProt A1ZA98. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether CG8425-PA [Drosophila melanogaster] is the right protein anchor across sources, using UniProt A1ZA98 as the stable mapping.
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| Preferred Name | CG8425-PA [Drosophila melanogaster] |
| Target Type | SINGLE PROTEIN |
| Organism | Drosophila melanogaster |
| UniProt | A1ZA98 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carboxylic ester hydrolase |
| UniProt Accession | A1ZA98 |
| Component Type | Protein |
| Sequence Length | 579 aa |
Carboxylic ester hydrolase
Review this target as CG8425-PA [Drosophila melanogaster], mapped to UniProt A1ZA98. ChEMBL maps the protein component as Carboxylic ester hydrolase. Sequence length is 579 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL155514 | 9.27 | IC50 | 0.537 | Preclinical |
| CHEMBL153015 | 8.28 | IC50 | 5.248 | Preclinical |
| CHEMBL440542 | 7.51 | IC50 | 30.9 | Preclinical |
| CHEMBL155513 | 7.44 | IC50 | 36.31 | Preclinical |
| CHEMBL153080 | 7.13 | IC50 | 74.13 | Preclinical |
| CHEMBL421992 | 7.08 | IC50 | 83.18 | Preclinical |
| CHEMBL155621 | 6.83 | IC50 | 147.91 | Preclinical |
| CHEMBL153177 | 6.46 | IC50 | 346.74 | Preclinical |
| CHEMBL356917 | 6.4 | IC50 | 398.11 | Preclinical |
| CHEMBL155396 | 5.85 | IC50 | 1412.54 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 21 | 6.3 |