Use UniProt A0A286XTF2 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4295527 Target Snapshot
G_PROTEIN_RECEP_F1_2 domain-containing protein · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-14Protein identity stays anchored to UniProt A0A286XTF2. Use UniProt A0A286XTF2 as the stable identity anchor, then attach disease evidence before program review.
Opioid receptor delta 1
Review this target as G_PROTEIN_RECEP_F1_2 domain-containing protein, mapped to UniProt A0A286XTF2. ChEMBL maps the protein component as Opioid receptor delta 1. Sequence length is 366 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats G_PROTEIN_RECEP_F1_2 domain-containing protein as ChEMBL target CHEMBL4295527, mapped to UniProt A0A286XTF2. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether G_PROTEIN_RECEP_F1_2 domain-containing protein is the right protein anchor across sources, using UniProt A0A286XTF2 as the stable mapping.
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| Preferred Name | G_PROTEIN_RECEP_F1_2 domain-containing protein |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | A0A286XTF2 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Opioid receptor delta 1 |
| UniProt Accession | A0A286XTF2 |
| Component Type | Protein |
| Sequence Length | 366 aa |
Opioid receptor delta 1
How to read this target
Review this target as G_PROTEIN_RECEP_F1_2 domain-containing protein, mapped to UniProt A0A286XTF2. ChEMBL maps the protein component as Opioid receptor delta 1. Sequence length is 366 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3085528 | 9.24 | Ki | 0.58 | Preclinical |
| CHEMBL289683 | 8.96 | Ki | 1.1 | Preclinical |
| CHEMBL2367604 | 8.6 | Ki | 2.5 | Preclinical |
| CHEMBL55033 | 8.47 | Ki | 3.4 | Preclinical |
| CHEMBL2367916 | 8.28 | Ki | 5.2 | Preclinical |
| CHEMBL297428 | 8.08 | Ki | 8.3 | Preclinical |
| CHEMBL4210742 | 8.08 | Ki | 8.3 | Preclinical |
| CHEMBL4215981 | 8.01 | Ki | 9.8 | Preclinical |
| CHEMBL461229 | 8.01 | Ki | 9.8 | Preclinical |
| CHEMBL2367918 | 7.92 | Ki | 12.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 4 assays, 14 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 3 | 14 | 8.0 |
| single protein format | 1 | 0 | — |