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Target Snapshot

CHEMBL4295538 Target Snapshot

Dipeptidyl peptidase 9 · SINGLE PROTEIN · Bos taurus

7Compounds
1Assays
1Approved Drugs
7.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt E1BI31. Use UniProt E1BI31 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt E1BI31 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Dipeptidyl peptidase 9 as ChEMBL target CHEMBL4295538, mapped to UniProt E1BI31. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Dipeptidyl peptidase 9
SINGLE PROTEIN · Bos taurus
As of 2026-09-13
ChEMBL target ID
CHEMBL4295538
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
E1BI31
dipeptidyl-peptidase IV
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Dipeptidyl peptidase 9 is the right protein anchor across sources, using UniProt E1BI31 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein Labeldipeptidyl-peptidase IV
UniProt AccessionE1BI31
Component TypeProtein
Sequence Length877 aa

dipeptidyl-peptidase IV

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Dipeptidyl peptidase 9, mapped to UniProt E1BI31. ChEMBL maps the protein component as dipeptidyl-peptidase IV. Sequence length is 877 aa.

Mapped IDE1BI31
Review nameDipeptidyl peptidase 9
OrganismBos taurus
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

IC507.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL397070 6.54 IC50 290.0 Preclinical
CHEMBL142703 6.17 IC50 680.0 Approved
CHEMBL98408 5.18 IC50 6600.0 Preclinical
CHEMBL383705 4.95 IC50 11300.0 Preclinical
CHEMBL98869 4.12 IC50 76600.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
0
5.5
1
6.0
1
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

VILDAGLIPTIN
CHEMBL142703
Approved 2007
Assay Landscape

Assay Landscape

1
Total Assays
5
Tested Compounds
1
Assay Types
Binding — 1 assays, 5 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 1 5 5.4

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine