G_PROTEIN_RECEP_F1_2 domain-containing protein · SINGLE PROTEIN · Macaca mulatta
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As of 2026-09-14Protein identity stays anchored to UniProt F7HEV7. Use UniProt F7HEV7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt F7HEV7 as the stable identity anchor, then attach disease evidence before program review.
Mu-type opioid receptor
Review this target as G_PROTEIN_RECEP_F1_2 domain-containing protein, mapped to UniProt F7HEV7. ChEMBL maps the protein component as Mu-type opioid receptor. Sequence length is 372 aa.
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This review treats G_PROTEIN_RECEP_F1_2 domain-containing protein as ChEMBL target CHEMBL4295544, mapped to UniProt F7HEV7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | G_PROTEIN_RECEP_F1_2 domain-containing protein |
| Target Type | SINGLE PROTEIN |
| Organism | Macaca mulatta |
| UniProt | F7HEV7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mu-type opioid receptor |
| UniProt Accession | F7HEV7 |
| Component Type | Protein |
| Sequence Length | 372 aa |
Mu-type opioid receptor
Review this target as G_PROTEIN_RECEP_F1_2 domain-containing protein, mapped to UniProt F7HEV7. ChEMBL maps the protein component as Mu-type opioid receptor. Sequence length is 372 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4204891 | 8.38 | Ki | 4.2 | Preclinical |
| CHEMBL98883 | 8.26 | Ki | 5.5 | Preclinical |
| CHEMBL4207341 | 8.24 | Ki | 5.8 | Preclinical |
| CHEMBL4209962 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL4214248 | 7.68 | Ki | 21.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 1 | 5 | 8.1 |