Protease · SINGLE PROTEIN · Norovirus Hu/GII.4-2002/WeertE022/2002/NL
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt G1FEK8. Use UniProt G1FEK8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt G1FEK8 as the stable identity anchor, then attach disease evidence before program review.
Genome polyprotein
Review this target as Protease, mapped to UniProt G1FEK8. ChEMBL maps the protein component as Genome polyprotein. Sequence length is 181 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protease as ChEMBL target CHEMBL4295547, mapped to UniProt G1FEK8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protease |
| Target Type | SINGLE PROTEIN |
| Organism | Norovirus Hu/GII.4-2002/WeertE022/2002/NL |
| UniProt | G1FEK8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Genome polyprotein |
| UniProt Accession | G1FEK8 |
| Component Type | Protein |
| Sequence Length | 181 aa |
Genome polyprotein
Review this target as Protease, mapped to UniProt G1FEK8. ChEMBL maps the protein component as Genome polyprotein. Sequence length is 181 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2441741 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL4129318 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL4128485 | 6.3 | IC50 | 502.0 | Preclinical |
| CHEMBL4128616 | 5.93 | IC50 | 1170.0 | Preclinical |
| CHEMBL4127236 | 5.58 | IC50 | 2630.0 | Preclinical |
| CHEMBL4128223 | 5.58 | IC50 | 2630.0 | Preclinical |
| CHEMBL4128073 | 4.52 | IC50 | 30000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 7 | 6.0 |