Dipeptidyl peptidase IV · SINGLE PROTEIN · Porphyromonas gingivalis
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As of 2026-09-14Protein identity stays anchored to UniProt O31048. Use UniProt O31048 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O31048 as the stable identity anchor, then attach disease evidence before program review.
Dipeptidyl peptidase IV
Review this target as Dipeptidyl peptidase IV, mapped to UniProt O31048. Sequence length is 723 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dipeptidyl peptidase IV as ChEMBL target CHEMBL4295559, mapped to UniProt O31048. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dipeptidyl peptidase IV |
| Target Type | SINGLE PROTEIN |
| Organism | Porphyromonas gingivalis |
| UniProt | O31048 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dipeptidyl peptidase IV |
| UniProt Accession | O31048 |
| Component Type | Protein |
| Sequence Length | 723 aa |
Dipeptidyl peptidase IV
Review this target as Dipeptidyl peptidase IV, mapped to UniProt O31048. Sequence length is 723 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL142703 | 7.77 | Ki | 17.0 | Approved |
| CHEMBL4175831 | 7.1 | IC50 | 79.0 | Preclinical |
| CHEMBL4176189 | 6.85 | IC50 | 140.0 | Preclinical |
| CHEMBL471547 | 6.64 | IC50 | 230.0 | Preclinical |
| CHEMBL471747 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL471546 | 6.51 | IC50 | 310.0 | Preclinical |
| CHEMBL471731 | 6.48 | IC50 | 330.0 | Preclinical |
| CHEMBL4168495 | 6.32 | IC50 | 480.0 | Preclinical |
| CHEMBL4169745 | 6.24 | IC50 | 580.0 | Preclinical |
| CHEMBL4167565 | 6.1 | IC50 | 800.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 30 | 5.5 |