Use UniProt O66465 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4295560 Target Snapshot
Phospho-N-acetylmuramoyl-pentapeptide-transferase · SINGLE PROTEIN · Aquifex aeolicus (strain VF5)
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As of 2026-09-14Protein identity stays anchored to UniProt O66465. Use UniProt O66465 as the stable identity anchor, then attach disease evidence before program review.
Phospho-N-acetylmuramoyl-pentapeptide-transferase
Review this target as Phospho-N-acetylmuramoyl-pentapeptide-transferase, mapped to UniProt O66465. Sequence length is 359 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Phospho-N-acetylmuramoyl-pentapeptide-transferase as ChEMBL target CHEMBL4295560, mapped to UniProt O66465. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phospho-N-acetylmuramoyl-pentapeptide-transferase |
| Target Type | SINGLE PROTEIN |
| Organism | Aquifex aeolicus (strain VF5) |
| UniProt | O66465 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phospho-N-acetylmuramoyl-pentapeptide-transferase |
| UniProt Accession | O66465 |
| Component Type | Protein |
| Sequence Length | 359 aa |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
How to read this target
Review this target as Phospho-N-acetylmuramoyl-pentapeptide-transferase, mapped to UniProt O66465. Sequence length is 359 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4279378 | 9.49 | IC50 | 0.32 | Preclinical |
| CHEMBL4286766 | 9.46 | IC50 | 0.35 | Preclinical |
| CHEMBL4592367 | 4.82 | IC50 | 15000.0 | Preclinical |
| CHEMBL4441639 | 4.7 | IC50 | 20000.0 | Preclinical |
| CHEMBL4521972 | 4.7 | IC50 | 20000.0 | Preclinical |
| CHEMBL4452848 | 4.6 | IC50 | 25000.0 | Preclinical |
| CHEMBL4524781 | 4.6 | IC50 | 25000.0 | Preclinical |
| CHEMBL4565456 | 4.6 | IC50 | 25000.0 | Preclinical |
| CHEMBL4577355 | 4.52 | IC50 | 30000.0 | Preclinical |
| CHEMBL4555507 | 4.46 | IC50 | 35000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 3 assays, 25 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 22 | 4.4 |
| assay format | 1 | 3 | 9.5 |