Leucine--tRNA ligase · SINGLE PROTEIN · Escherichia coli (strain K12)
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P07813. Use UniProt P07813 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P07813 as the stable identity anchor, then attach disease evidence before program review.
Leucine--tRNA ligase
Review this target as Leucine--tRNA ligase, mapped to UniProt P07813. Sequence length is 860 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Leucine--tRNA ligase as ChEMBL target CHEMBL4295566, mapped to UniProt P07813. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Leucine--tRNA ligase |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli (strain K12) |
| UniProt | P07813 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Leucine--tRNA ligase |
| UniProt Accession | P07813 |
| Component Type | Protein |
| Sequence Length | 860 aa |
Leucine--tRNA ligase
Review this target as Leucine--tRNA ligase, mapped to UniProt P07813. Sequence length is 860 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1163081 | 9.86 | Ki | 0.139 | Preclinical |
| CHEMBL4204314 | 9.18 | Ki | 0.654 | Preclinical |
| CHEMBL4160841 | 8.89 | Kd | 1.3 | Preclinical |
| CHEMBL4444740 | 8.85 | Kd | 1.4 | Preclinical |
| CHEMBL4864835 | 8.61 | Ki | 2.48 | Preclinical |
| CHEMBL4869028 | 8.26 | Ki | 5.51 | Preclinical |
| CHEMBL4465674 | 8.01 | Ki | 9.8 | Preclinical |
| CHEMBL4163450 | 8.0 | Kd | 10.0 | Preclinical |
| CHEMBL4171058 | 7.99 | Kd | 10.2 | Preclinical |
| CHEMBL4163140 | 7.96 | Kd | 10.9 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 13 | 28 | 7.7 |
| cell-based format | 1 | 10 | 7.4 |