Alternative oxidase, mitochondrial · SINGLE PROTEIN · Trypanosoma brucei brucei
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As of 2026-09-14Protein identity stays anchored to UniProt Q26710. Use UniProt Q26710 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q26710 as the stable identity anchor, then attach disease evidence before program review.
Alternative oxidase, mitochondrial
Review this target as Alternative oxidase, mitochondrial, mapped to UniProt Q26710. Sequence length is 329 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Alternative oxidase, mitochondrial as ChEMBL target CHEMBL4295594, mapped to UniProt Q26710. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Alternative oxidase, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Trypanosoma brucei brucei |
| UniProt | Q26710 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Alternative oxidase, mitochondrial |
| UniProt Accession | Q26710 |
| Component Type | Protein |
| Sequence Length | 329 aa |
Alternative oxidase, mitochondrial
Review this target as Alternative oxidase, mitochondrial, mapped to UniProt Q26710. Sequence length is 329 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL133046 | 9.89 | Ki | 0.13 | Preclinical |
| CHEMBL4879019 | 8.8 | IC50 | 1.6 | Preclinical |
| CHEMBL133046 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL4294528 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL4216944 | 8.51 | IC50 | 3.1 | Preclinical |
| CHEMBL4291644 | 8.4 | IC50 | 3.981 | Preclinical |
| CHEMBL4213740 | 8.38 | IC50 | 4.2 | Preclinical |
| CHEMBL4203629 | 8.04 | IC50 | 9.1 | Preclinical |
| CHEMBL4205799 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL4215836 | 7.82 | IC50 | 15.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 18 | 6.7 |
| single protein format | 2 | 25 | 6.7 |
| cell-based format | 1 | 1 | 5.3 |