Inosine-5'-monophosphate dehydrogenase · SINGLE PROTEIN · Cryptococcus neoformans var. neoformans serotype D (strain JEC21 /ATCC MYA-565) (Filobasidiella neoformans)
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As of 2026-09-14Protein identity stays anchored to UniProt Q5KP44. Use UniProt Q5KP44 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q5KP44 as the stable identity anchor, then attach disease evidence before program review.
Inosine-5'-monophosphate dehydrogenase
Review this target as Inosine-5'-monophosphate dehydrogenase, mapped to UniProt Q5KP44. Sequence length is 544 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Inosine-5'-monophosphate dehydrogenase as ChEMBL target CHEMBL4295605, mapped to UniProt Q5KP44. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Inosine-5'-monophosphate dehydrogenase |
| Target Type | SINGLE PROTEIN |
| Organism | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 /ATCC MYA-565) (Filobasidiella neoformans) |
| UniProt | Q5KP44 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Inosine-5'-monophosphate dehydrogenase |
| UniProt Accession | Q5KP44 |
| Component Type | Protein |
| Sequence Length | 544 aa |
Inosine-5'-monophosphate dehydrogenase
Review this target as Inosine-5'-monophosphate dehydrogenase, mapped to UniProt Q5KP44. Sequence length is 544 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL866 | 6.92 | IC50 | 120.0 | Approved |
| CHEMBL4277486 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL4289187 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL4288538 | 6.64 | IC50 | 230.0 | Preclinical |
| CHEMBL4277233 | 6.47 | IC50 | 340.0 | Preclinical |
| CHEMBL1602759 | 6.43 | IC50 | 370.0 | Preclinical |
| CHEMBL4280641 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL4176498 | 6.39 | IC50 | 410.0 | Preclinical |
| CHEMBL4284098 | 6.32 | IC50 | 480.0 | Preclinical |
| CHEMBL4166303 | 6.31 | IC50 | 490.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 38 | 16 | 6.4 |