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Target Snapshot

CHEMBL4295614 Target Snapshot

Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 · SINGLE PROTEIN · Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 /NCIMB 9373 / NRRL B-3711)

1Compounds
4Assays
0Approved Drugs
2.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q81EJ6. Use UniProt Q81EJ6 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q81EJ6 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 as ChEMBL target CHEMBL4295614, mapped to UniProt Q81EJ6. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Peptidoglycan-N-acetylglucosamine deacetylase BC_1974
SINGLE PROTEIN · Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 /NCIMB 9373 / NRRL B-3711)
As of 2026-09-14
ChEMBL target ID
CHEMBL4295614
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q81EJ6
Peptidoglycan-N-acetylglucosamine deacetylase BC_1974
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 is the right protein anchor across sources, using UniProt Q81EJ6 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPeptidoglycan-N-acetylglucosamine deacetylase BC_1974
UniProt AccessionQ81EJ6
Component TypeProtein
Sequence Length273 aa

Peptidoglycan-N-acetylglucosamine deacetylase BC_1974

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Peptidoglycan-N-acetylglucosamine deacetylase BC_1974, mapped to UniProt Q81EJ6. Sequence length is 273 aa.

Mapped IDQ81EJ6
Review namePeptidoglycan-N-acetylglucosamine deacetylase BC_1974
OrganismBacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 /NCIMB 9373 / NRRL B-3711)
Assay Mix

Activity Type Distribution

IC501.0
KI1.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL156887 5.06 Ki 8700.0 Preclinical
CHEMBL156887 4.36 IC50 43300.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

4
Total Assays
1
Tested Compounds
1
Assay Types
Binding — 4 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 4 1 4.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine