Polyprotein P1234 · SINGLE PROTEIN · Chikungunya virus (strain S27-African prototype) (CHIKV)
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As of 2026-09-14Protein identity stays anchored to UniProt Q8JUX6. Use UniProt Q8JUX6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8JUX6 as the stable identity anchor, then attach disease evidence before program review.
Polyprotein P1234
Review this target as Polyprotein P1234, mapped to UniProt Q8JUX6. Sequence length is 2474 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Polyprotein P1234 as ChEMBL target CHEMBL4295622, mapped to UniProt Q8JUX6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Polyprotein P1234 |
| Target Type | SINGLE PROTEIN |
| Organism | Chikungunya virus (strain S27-African prototype) (CHIKV) |
| UniProt | Q8JUX6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Polyprotein P1234 |
| UniProt Accession | Q8JUX6 |
| Component Type | Protein |
| Sequence Length | 2474 aa |
Polyprotein P1234
Review this target as Polyprotein P1234, mapped to UniProt Q8JUX6. Sequence length is 2474 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5591218 | 7.6 | IC50 | 25.12 | Preclinical |
| CHEMBL5594820 | 7.6 | IC50 | 25.12 | Preclinical |
| CHEMBL5594389 | 7.5 | IC50 | 31.62 | Preclinical |
| CHEMBL5592235 | 7.4 | IC50 | 39.81 | Preclinical |
| CHEMBL5593311 | 7.4 | IC50 | 39.81 | Preclinical |
| CHEMBL5593311 | 7.4 | Ki | 39.81 | Preclinical |
| CHEMBL5590710 | 7.3 | IC50 | 50.12 | Preclinical |
| CHEMBL5591355 | 7.3 | IC50 | 50.12 | Preclinical |
| CHEMBL5594031 | 7.3 | IC50 | 50.12 | Preclinical |
| CHEMBL5594644 | 7.22 | IC50 | 60.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 4 | 4.9 |
| assay format | 4 | 72 | 6.3 |
| cell-based format | 1 | 2 | 5.4 |