Cell cycle histidine kinase CckA · SINGLE PROTEIN · Caulobacter vibrioides
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As of 2026-09-15Protein identity stays anchored to UniProt Q9X688. Use UniProt Q9X688 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9X688 as the stable identity anchor, then attach disease evidence before program review.
histidine kinase
Review this target as Cell cycle histidine kinase CckA, mapped to UniProt Q9X688. ChEMBL maps the protein component as histidine kinase. Sequence length is 691 aa.
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This review treats Cell cycle histidine kinase CckA as ChEMBL target CHEMBL4295627, mapped to UniProt Q9X688. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cell cycle histidine kinase CckA |
| Target Type | SINGLE PROTEIN |
| Organism | Caulobacter vibrioides |
| UniProt | Q9X688 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | histidine kinase |
| UniProt Accession | Q9X688 |
| Component Type | Protein |
| Sequence Length | 691 aa |
histidine kinase
Review this target as Cell cycle histidine kinase CckA, mapped to UniProt Q9X688. ChEMBL maps the protein component as histidine kinase. Sequence length is 691 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL371380 | 5.42 | Ki | 3800.0 | Preclinical |
| CHEMBL252164 | 5.14 | IC50 | 7300.0 | Clinical |
| CHEMBL191074 | 4.95 | IC50 | 11200.0 | Preclinical |
| CHEMBL371380 | 4.91 | IC50 | 12300.0 | Preclinical |
| CHEMBL364882 | 4.76 | IC50 | 17500.0 | Preclinical |
| CHEMBL4218027 | 4.73 | IC50 | 18600.0 | Preclinical |
| CHEMBL399530 | 4.55 | IC50 | 28000.0 | Preclinical |
| CHEMBL191228 | 4.49 | IC50 | 32300.0 | Preclinical |
| CHEMBL4217100 | 4.49 | IC50 | 32700.0 | Preclinical |
| CHEMBL4204469 | 4.47 | IC50 | 33600.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 12 | 4.6 |
| single protein format | 1 | 1 | 5.4 |