Thiamine transporter ThiT · SINGLE PROTEIN · Lactococcus lactis subsp. cremoris (strain MG1363)
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As of 2026-09-14Protein identity stays anchored to UniProt A2RI47. Use UniProt A2RI47 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A2RI47 as the stable identity anchor, then attach disease evidence before program review.
Thiamine transporter ThiT
Review this target as Thiamine transporter ThiT, mapped to UniProt A2RI47. Sequence length is 182 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Thiamine transporter ThiT as ChEMBL target CHEMBL4295631, mapped to UniProt A2RI47. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Thiamine transporter ThiT |
| Target Type | SINGLE PROTEIN |
| Organism | Lactococcus lactis subsp. cremoris (strain MG1363) |
| UniProt | A2RI47 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Thiamine transporter ThiT |
| UniProt Accession | A2RI47 |
| Component Type | Protein |
| Sequence Length | 182 aa |
Thiamine transporter ThiT
Review this target as Thiamine transporter ThiT, mapped to UniProt A2RI47. Sequence length is 182 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1547 | 9.91 | Kd | 0.122 | Approved |
| CHEMBL1229798 | 9.74 | Kd | 0.18 | Preclinical |
| CHEMBL1236376 | 8.8 | Kd | 1.6 | Clinical |
| CHEMBL401772 | 8.37 | Kd | 4.23 | Preclinical |
| CHEMBL4291753 | 8.28 | Kd | 5.21 | Preclinical |
| CHEMBL4289112 | 7.7 | Kd | 20.1 | Preclinical |
| CHEMBL4281235 | 7.39 | Kd | 40.3 | Preclinical |
| CHEMBL4287450 | 7.01 | Kd | 96.7 | Preclinical |
| CHEMBL4284640 | 6.78 | Kd | 168.0 | Preclinical |
| CHEMBL4279528 | 6.74 | Kd | 183.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 9 | 17 | 7.2 |