Serine/threonine-protein kinase PAK 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt O88643. Use UniProt O88643 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O88643 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase PAK 1
Review this target as Serine/threonine-protein kinase PAK 1, mapped to UniProt O88643. Sequence length is 545 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase PAK 1 as ChEMBL target CHEMBL4295682, mapped to UniProt O88643. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serine/threonine-protein kinase PAK 1 is the right protein anchor across sources, using UniProt O88643 as the stable mapping.
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| Preferred Name | Serine/threonine-protein kinase PAK 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | O88643 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase PAK 1 |
| UniProt Accession | O88643 |
| Component Type | Protein |
| Sequence Length | 545 aa |
Serine/threonine-protein kinase PAK 1
Review this target as Serine/threonine-protein kinase PAK 1, mapped to UniProt O88643. Sequence length is 545 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5661936 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL299496 | 6.0 | IC50 | 1000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 1 | 6.0 |
| cell-based format | 2 | 1 | 7.2 |