Cathepsin L · SINGLE PROTEIN · Toxoplasma gondii
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As of 2026-09-14Protein identity stays anchored to UniProt Q6DMN0. Use UniProt Q6DMN0 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q6DMN0 as the stable identity anchor, then attach disease evidence before program review.
Cathepsin CPL
Review this target as Cathepsin L, mapped to UniProt Q6DMN0. ChEMBL maps the protein component as Cathepsin CPL. Sequence length is 422 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cathepsin L as ChEMBL target CHEMBL4295862, mapped to UniProt Q6DMN0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cathepsin L |
| Target Type | SINGLE PROTEIN |
| Organism | Toxoplasma gondii |
| UniProt | Q6DMN0 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cathepsin CPL |
| UniProt Accession | Q6DMN0 |
| Component Type | Protein |
| Sequence Length | 422 aa |
Cathepsin CPL
Review this target as Cathepsin L, mapped to UniProt Q6DMN0. ChEMBL maps the protein component as Cathepsin CPL. Sequence length is 422 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL222649 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL4126546 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL4125776 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL4126172 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL4128887 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL4129611 | 6.75 | IC50 | 180.0 | Preclinical |
| CHEMBL4130087 | 6.6 | IC50 | 250.0 | Preclinical |
| CHEMBL4129470 | 6.46 | IC50 | 350.0 | Preclinical |
| CHEMBL4128244 | 6.44 | IC50 | 360.0 | Preclinical |
| CHEMBL4130249 | 6.4 | IC50 | 400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 27 | 6.1 |