Falcilysin · SINGLE PROTEIN · Plasmodium falciparum (isolate 3D7)
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q76NL8. Use UniProt Q76NL8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q76NL8 as the stable identity anchor, then attach disease evidence before program review.
Falcilysin
Review this target as Falcilysin, mapped to UniProt Q76NL8. Sequence length is 1193 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Falcilysin as ChEMBL target CHEMBL4295876, mapped to UniProt Q76NL8. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Falcilysin is the right protein anchor across sources, using UniProt Q76NL8 as the stable mapping.
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| Preferred Name | Falcilysin |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum (isolate 3D7) |
| UniProt | Q76NL8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Falcilysin |
| UniProt Accession | Q76NL8 |
| Component Type | Protein |
| Sequence Length | 1193 aa |
Falcilysin
Review this target as Falcilysin, mapped to UniProt Q76NL8. Sequence length is 1193 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4799253 | 6.66 | Ki | 220.0 | Preclinical |
| CHEMBL4743280 | 6.22 | Ki | 600.0 | Preclinical |
| CHEMBL4782486 | 6.05 | Ki | 900.0 | Preclinical |
| CHEMBL4799260 | 6.0 | Ki | 1000.0 | Preclinical |
| CHEMBL4797916 | 5.96 | Ki | 1100.0 | Preclinical |
| CHEMBL4749474 | 5.85 | Ki | 1400.0 | Preclinical |
| CHEMBL4794156 | 5.85 | Ki | 1400.0 | Preclinical |
| CHEMBL4225532 | 5.82 | IC50 | 1500.0 | Preclinical |
| CHEMBL4785958 | 5.77 | Ki | 1700.0 | Preclinical |
| CHEMBL4741390 | 5.6 | Ki | 2500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 15 | 4.9 |
| single protein format | 1 | 22 | 5.6 |