Ubiquitin carboxyl-terminal hydrolase 25 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-15Protein identity stays anchored to UniProt Q9UHP3. Use UniProt Q9UHP3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UHP3 as the stable identity anchor, then attach disease evidence before program review.
Ubiquitin carboxyl-terminal hydrolase 25
Review this target as Ubiquitin carboxyl-terminal hydrolase 25, mapped to UniProt Q9UHP3. Sequence length is 1055 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ubiquitin carboxyl-terminal hydrolase 25 as ChEMBL target CHEMBL4295975, mapped to UniProt Q9UHP3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ubiquitin carboxyl-terminal hydrolase 25 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UHP3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ubiquitin carboxyl-terminal hydrolase 25 |
| UniProt Accession | Q9UHP3 |
| Component Type | Protein |
| Sequence Length | 1055 aa |
Ubiquitin carboxyl-terminal hydrolase 25
Review this target as Ubiquitin carboxyl-terminal hydrolase 25, mapped to UniProt Q9UHP3. Sequence length is 1055 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4174196 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4300392 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4443504 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4451295 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4459980 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4462420 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4483621 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4513397 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4514285 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4514361 | 6.7 | IC50 | 200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 12 | 216 | 5.9 |
| cell-based format | 4 | 4 | 6.0 |
| assay format | 2 | 0 | — |