MAPK/MAK/MRK overlapping kinase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UQ07. Use UniProt Q9UQ07 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UQ07 as the stable identity anchor, then attach disease evidence before program review.
MAPK/MAK/MRK overlapping kinase
Review this target as MAPK/MAK/MRK overlapping kinase, mapped to UniProt Q9UQ07. Sequence length is 419 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats MAPK/MAK/MRK overlapping kinase as ChEMBL target CHEMBL4295983, mapped to UniProt Q9UQ07. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | MAPK/MAK/MRK overlapping kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UQ07 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | MAPK/MAK/MRK overlapping kinase |
| UniProt Accession | Q9UQ07 |
| Component Type | Protein |
| Sequence Length | 419 aa |
MAPK/MAK/MRK overlapping kinase
Review this target as MAPK/MAK/MRK overlapping kinase, mapped to UniProt Q9UQ07. Sequence length is 419 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5879765 | 8.7 | Kd | 2.0 | Preclinical |
| CHEMBL6005155 | 8.52 | Kd | 3.0 | Preclinical |
| CHEMBL5796991 | 8.1 | Kd | 8.0 | Preclinical |
| CHEMBL5881386 | 8.0 | Kd | 10.0 | Preclinical |
| CHEMBL5971800 | 7.96 | Kd | 11.0 | Preclinical |
| CHEMBL5758869 | 7.89 | Kd | 13.0 | Preclinical |
| CHEMBL6042160 | 7.8 | Kd | 16.0 | Preclinical |
| CHEMBL6044780 | 7.66 | Kd | 22.0 | Preclinical |
| CHEMBL5859519 | 7.6 | Kd | 25.0 | Preclinical |
| CHEMBL6040216 | 7.57 | Kd | 27.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 24 | 31 | 7.3 |
| assay format | 1 | 13 | 4.5 |