2-Hydroxyacid oxidase 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9WU19. Use UniProt Q9WU19 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9WU19 as the stable identity anchor, then attach disease evidence before program review.
2-Hydroxyacid oxidase 1
Review this target as 2-Hydroxyacid oxidase 1, mapped to UniProt Q9WU19. Sequence length is 370 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 2-Hydroxyacid oxidase 1 as ChEMBL target CHEMBL4295985, mapped to UniProt Q9WU19. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 2-Hydroxyacid oxidase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9WU19 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 2-Hydroxyacid oxidase 1 |
| UniProt Accession | Q9WU19 |
| Component Type | Protein |
| Sequence Length | 370 aa |
2-Hydroxyacid oxidase 1
Review this target as 2-Hydroxyacid oxidase 1, mapped to UniProt Q9WU19. Sequence length is 370 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4864519 | 8.11 | IC50 | 7.7 | Preclinical |
| CHEMBL4857427 | 7.84 | IC50 | 14.6 | Preclinical |
| CHEMBL5170581 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL5204083 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL5180187 | 5.75 | IC50 | 1800.0 | Preclinical |
| CHEMBL4245703 | 5.54 | IC50 | 2900.0 | Preclinical |
| CHEMBL5182027 | 5.51 | IC50 | 3100.0 | Preclinical |
| CHEMBL4242089 | 5.46 | IC50 | 3500.0 | Preclinical |
| CHEMBL4247590 | 5.46 | EC50 | 3450.0 | Preclinical |
| CHEMBL4237565 | 5.45 | EC50 | 3590.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 21 | 10 | 5.2 |
| assay format | 5 | 27 | 5.0 |
| tissue-based format | 1 | 1 | 5.3 |