Cyclin-dependent kinase 1/ G1/S-specific cyclin-D3 · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P06493. Use UniProt P06493 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P06493 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 1
Review this target as Cyclin-dependent kinase 1/ G1/S-specific cyclin-D3, mapped to UniProt P06493. ChEMBL maps the protein component as Cyclin-dependent kinase 1. Sequence length is 297 aa.
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This review treats Cyclin-dependent kinase 1/ G1/S-specific cyclin-D3 as ChEMBL target CHEMBL4296065, mapped to UniProt P06493. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cyclin-dependent kinase 1/ G1/S-specific cyclin-D3 |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P06493 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 1 |
| UniProt Accession | P06493 |
| Component Type | Protein |
| Sequence Length | 297 aa |
Cyclin-dependent kinase 1
Review this target as Cyclin-dependent kinase 1/ G1/S-specific cyclin-D3, mapped to UniProt P06493. ChEMBL maps the protein component as Cyclin-dependent kinase 1. Sequence length is 297 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4289226 | 9.62 | IC50 | 0.24 | Preclinical |
| CHEMBL4277525 | 9.38 | IC50 | 0.42 | Preclinical |
| CHEMBL4279832 | 9.37 | IC50 | 0.43 | Preclinical |
| CHEMBL4287693 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL4287743 | 9.02 | IC50 | 0.96 | Preclinical |
| CHEMBL4281514 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4294940 | 8.96 | IC50 | 1.09 | Preclinical |
| CHEMBL4284301 | 8.76 | IC50 | 1.74 | Preclinical |
| CHEMBL4285830 | 8.59 | IC50 | 2.56 | Preclinical |
| CHEMBL4286100 | 8.55 | IC50 | 2.83 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 24 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 1 | 20 | 8.3 |