CaM kinase II alpha/beta · PROTEIN COMPLEX · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P11275. Use UniProt P11275 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P11275 as the stable identity anchor, then attach disease evidence before program review.
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Review this target as CaM kinase II alpha/beta, mapped to UniProt P11275. ChEMBL maps the protein component as Calcium/calmodulin-dependent protein kinase type II subunit alpha. Sequence length is 478 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats CaM kinase II alpha/beta as ChEMBL target CHEMBL4296089, mapped to UniProt P11275. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | CaM kinase II alpha/beta |
| Target Type | PROTEIN COMPLEX |
| Organism | Rattus norvegicus |
| UniProt | P11275 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| UniProt Accession | P11275 |
| Component Type | Protein |
| Sequence Length | 478 aa |
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Review this target as CaM kinase II alpha/beta, mapped to UniProt P11275. ChEMBL maps the protein component as Calcium/calmodulin-dependent protein kinase type II subunit alpha. Sequence length is 478 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4215300 | 6.92 | EC50 | 120.0 | Preclinical |
| CHEMBL4210359 | 6.56 | EC50 | 274.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 1 | 2 | 6.7 |