Use UniProt P15791 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4296090 Target Snapshot
CaM kinase II delta/gamma · PROTEIN COMPLEX · Rattus norvegicus
Research home keeps recent targets
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Switch target
Move to another high-traffic target or paste a specific ChEMBL target ID.
Frame the target before identity details
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P15791. Use UniProt P15791 as the stable identity anchor, then attach disease evidence before program review.
Calcium/calmodulin-dependent protein kinase type II subunit delta
Review this target as CaM kinase II delta/gamma, mapped to UniProt P15791. ChEMBL maps the protein component as Calcium/calmodulin-dependent protein kinase type II subunit delta. Sequence length is 533 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats CaM kinase II delta/gamma as ChEMBL target CHEMBL4296090, mapped to UniProt P15791. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Start with the right source
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether CaM kinase II delta/gamma is the right protein anchor across sources, using UniProt P15791 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
Verify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | CaM kinase II delta/gamma |
| Target Type | PROTEIN COMPLEX |
| Organism | Rattus norvegicus |
| UniProt | P15791 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Calcium/calmodulin-dependent protein kinase type II subunit delta |
| UniProt Accession | P15791 |
| Component Type | Protein |
| Sequence Length | 533 aa |
Calcium/calmodulin-dependent protein kinase type II subunit delta
How to read this target
Review this target as CaM kinase II delta/gamma, mapped to UniProt P15791. ChEMBL maps the protein component as Calcium/calmodulin-dependent protein kinase type II subunit delta. Sequence length is 533 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4210359 | 8.21 | EC50 | 6.2 | Preclinical |
| CHEMBL4215300 | 8.13 | EC50 | 7.4 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 2 | 8.2 |