Cereblon/Casein kinase I alpha · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P48729. Use UniProt P48729 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P48729 as the stable identity anchor, then attach disease evidence before program review.
Casein kinase I isoform alpha
Review this target as Cereblon/Casein kinase I alpha, mapped to UniProt P48729. ChEMBL maps the protein component as Casein kinase I isoform alpha. Sequence length is 337 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cereblon/Casein kinase I alpha as ChEMBL target CHEMBL4296102, mapped to UniProt P48729. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cereblon/Casein kinase I alpha |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P48729 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Casein kinase I isoform alpha |
| UniProt Accession | P48729 |
| Component Type | Protein |
| Sequence Length | 337 aa |
Casein kinase I isoform alpha
Review this target as Cereblon/Casein kinase I alpha, mapped to UniProt P48729. ChEMBL maps the protein component as Casein kinase I isoform alpha. Sequence length is 337 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5395344 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5400246 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5401739 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5424205 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5426981 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5427472 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5434155 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5436432 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5436826 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5441130 | 9.0 | EC50 | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 27 | 10 | 9.0 |