HIF1A/p300/CREB-binding protein · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q09472. Use UniProt Q09472 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q09472 as the stable identity anchor, then attach disease evidence before program review.
Histone acetyltransferase p300
Review this target as HIF1A/p300/CREB-binding protein, mapped to UniProt Q09472. ChEMBL maps the protein component as Histone acetyltransferase p300. Sequence length is 2414 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats HIF1A/p300/CREB-binding protein as ChEMBL target CHEMBL4296108, mapped to UniProt Q09472. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether HIF1A/p300/CREB-binding protein is the right protein anchor across sources, using UniProt Q09472 as the stable mapping.
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| Preferred Name | HIF1A/p300/CREB-binding protein |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | Q09472 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone acetyltransferase p300 |
| UniProt Accession | Q09472 |
| Component Type | Protein |
| Sequence Length | 2414 aa |
Histone acetyltransferase p300
Review this target as HIF1A/p300/CREB-binding protein, mapped to UniProt Q09472. ChEMBL maps the protein component as Histone acetyltransferase p300. Sequence length is 2414 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL333985 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL4126974 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL4466328 | 5.28 | Kd | 5300.0 | Preclinical |
| CHEMBL4128348 | 5.2 | IC50 | 6300.0 | Preclinical |
| CHEMBL4129341 | 4.19 | IC50 | 65000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 4 | 5.2 |
| assay format | 1 | 1 | 5.3 |