Protein cereblon/DNA damage-binding protein 1/Bromodomain-containing protein 4 · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O60885. Use UniProt O60885 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O60885 as the stable identity anchor, then attach disease evidence before program review.
Bromodomain-containing protein 4
Review this target as Protein cereblon/DNA damage-binding protein 1/Bromodomain-containing protein 4, mapped to UniProt O60885. ChEMBL maps the protein component as Bromodomain-containing protein 4. Sequence length is 1362 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein cereblon/DNA damage-binding protein 1/Bromodomain-containing protein 4 as ChEMBL target CHEMBL4296145, mapped to UniProt O60885. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein cereblon/DNA damage-binding protein 1/Bromodomain-containing protein 4 |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | O60885 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Bromodomain-containing protein 4 |
| UniProt Accession | O60885 |
| Component Type | Protein |
| Sequence Length | 1362 aa |
Bromodomain-containing protein 4
Review this target as Protein cereblon/DNA damage-binding protein 1/Bromodomain-containing protein 4, mapped to UniProt O60885. ChEMBL maps the protein component as Bromodomain-containing protein 4. Sequence length is 1362 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5938943 | 8.14 | IC50 | 7.21 | Preclinical |
| CHEMBL5904309 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL5883980 | 7.88 | IC50 | 13.2 | Preclinical |
| CHEMBL4303781 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL5899236 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL4094346 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL6046370 | 7.61 | IC50 | 24.5 | Preclinical |
| CHEMBL5801330 | 7.57 | IC50 | 26.9 | Preclinical |
| CHEMBL5919906 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL6028267 | 7.51 | IC50 | 31.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 0 | — |
| protein format | 2 | 37 | 6.7 |