Envelope phospholipase OPG057 · SINGLE PROTEIN · Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))
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As of 2026-09-14Protein identity stays anchored to UniProt P04021. Use UniProt P04021 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P04021 as the stable identity anchor, then attach disease evidence before program review.
Envelope phospholipase OPG057
Review this target as Envelope phospholipase OPG057, mapped to UniProt P04021. Sequence length is 372 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Envelope phospholipase OPG057 as ChEMBL target CHEMBL4296170, mapped to UniProt P04021. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Envelope phospholipase OPG057 |
| Target Type | SINGLE PROTEIN |
| Organism | Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR)) |
| UniProt | P04021 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Envelope phospholipase OPG057 |
| UniProt Accession | P04021 |
| Component Type | Protein |
| Sequence Length | 372 aa |
Envelope phospholipase OPG057
Review this target as Envelope phospholipase OPG057, mapped to UniProt P04021. Sequence length is 372 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1257073 | 8.57 | IC50 | 2.66 | Approved |
| CHEMBL4864184 | 6.88 | IC50 | 133.0 | Preclinical |
| CHEMBL4867155 | 6.67 | IC50 | 216.0 | Preclinical |
| CHEMBL4871145 | 6.57 | IC50 | 270.0 | Preclinical |
| CHEMBL4878636 | 6.29 | IC50 | 515.0 | Preclinical |
| CHEMBL4850454 | 5.97 | IC50 | 1070.0 | Preclinical |
| CHEMBL4872088 | 5.78 | IC50 | 1660.0 | Preclinical |
| CHEMBL4857491 | 5.55 | IC50 | 2800.0 | Preclinical |
| CHEMBL4865942 | 5.51 | IC50 | 3060.0 | Preclinical |
| CHEMBL4852852 | 5.45 | IC50 | 3520.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 19 | 5.7 |