Connector enhancer of kinase suppressor of ras 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q969H4. Use UniProt Q969H4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q969H4 as the stable identity anchor, then attach disease evidence before program review.
Connector enhancer of kinase suppressor of ras 1
Review this target as Connector enhancer of kinase suppressor of ras 1, mapped to UniProt Q969H4. Sequence length is 720 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Connector enhancer of kinase suppressor of ras 1 as ChEMBL target CHEMBL4296242, mapped to UniProt Q969H4. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Connector enhancer of kinase suppressor of ras 1 is the right protein anchor across sources, using UniProt Q969H4 as the stable mapping.
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| Preferred Name | Connector enhancer of kinase suppressor of ras 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q969H4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Connector enhancer of kinase suppressor of ras 1 |
| UniProt Accession | Q969H4 |
| Component Type | Protein |
| Sequence Length | 720 aa |
Connector enhancer of kinase suppressor of ras 1
Review this target as Connector enhancer of kinase suppressor of ras 1, mapped to UniProt Q969H4. Sequence length is 720 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4540854 | 9.71 | Kd | 0.196 | Preclinical |
| CHEMBL4528582 | 7.58 | Kd | 26.0 | Preclinical |
| CHEMBL4451466 | 6.8 | Kd | 157.0 | Preclinical |
| CHEMBL4293794 | 6.73 | Kd | 186.0 | Preclinical |
| CHEMBL4576938 | 6.57 | Kd | 270.0 | Preclinical |
| CHEMBL4441711 | 6.52 | Kd | 300.0 | Preclinical |
| CHEMBL4578514 | 6.52 | Kd | 300.0 | Preclinical |
| CHEMBL4451129 | 6.21 | Kd | 614.0 | Preclinical |
| CHEMBL4464276 | 6.19 | Kd | 650.0 | Preclinical |
| CHEMBL4473657 | 6.16 | Kd | 700.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 22 | 0 | — |
| single protein format | 5 | 41 | 5.5 |
| assay format | 3 | 12 | 4.9 |