DNA-directed RNA polymerase subunit beta · SINGLE PROTEIN · Escherichia coli O127:H6 (strain E2348/69 / EPEC)
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As of 2026-09-14Protein identity stays anchored to UniProt B7UPE2. Use UniProt B7UPE2 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt B7UPE2 as the stable identity anchor, then attach disease evidence before program review.
DNA-directed RNA polymerase subunit beta
Review this target as DNA-directed RNA polymerase subunit beta, mapped to UniProt B7UPE2. Sequence length is 1342 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DNA-directed RNA polymerase subunit beta as ChEMBL target CHEMBL4296294, mapped to UniProt B7UPE2. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | DNA-directed RNA polymerase subunit beta |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli O127:H6 (strain E2348/69 / EPEC) |
| UniProt | B7UPE2 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | DNA-directed RNA polymerase subunit beta |
| UniProt Accession | B7UPE2 |
| Component Type | Protein |
| Sequence Length | 1342 aa |
DNA-directed RNA polymerase subunit beta
Review this target as DNA-directed RNA polymerase subunit beta, mapped to UniProt B7UPE2. Sequence length is 1342 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2046886 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL2046887 | 4.89 | IC50 | 13000.0 | Preclinical |
| CHEMBL2046885 | 4.46 | IC50 | 35000.0 | Preclinical |
| CHEMBL236297 | 4.2 | IC50 | 63000.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 5 | 4.5 |