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Target Snapshot

CHEMBL4296507 Target Snapshot

U2932 · CELL-LINE · Homo sapiens

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90Compounds
43Assays
2Approved Drugs
50.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats U2932 as ChEMBL target CHEMBL4296507. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
U2932
CELL-LINE · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL4296507
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether U2932 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameU2932
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelU2932
UniProt AccessionN/A

U2932

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as U2932.

Review nameU2932
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

2
Approved
1
Phase III
Assay Mix

Activity Type Distribution

IC5047.0
EC503.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL67 9.05 IC50 0.89 Preclinical
CHEMBL2103840 7.96 IC50 11.0 Clinical
CHEMBL4462577 7.75 IC50 17.7 Preclinical
CHEMBL5400566 7.68 IC50 21.0 Preclinical
CHEMBL4540226 7.52 IC50 30.0 Preclinical
CHEMBL5406266 7.35 IC50 45.0 Preclinical
CHEMBL5416120 7.35 IC50 45.0 Preclinical
CHEMBL5191222 7.11 IC50 77.0 Preclinical
CHEMBL5426640 7.01 IC50 98.0 Preclinical
CHEMBL5419105 6.98 IC50 104.0 Preclinical
Distribution

pChEMBL Value Distribution

3
5.0
7
5.5
9
6.0
18
6.5
4
7.0
4
7.5
0
8.0
0
8.5
1
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

43
Total Assays
44
Tested Compounds
1
Assay Types
Functional — 43 assays, 44 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 32 44 6.6
organism-based format 11 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine