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Target Snapshot

CHEMBL4296518 Target Snapshot

Erythrocyte · CELL-LINE

Back to Search Search this target Browse approvals Evidence Card
5,213Compounds
1,042Assays
3Approved Drugs
497.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Erythrocyte as ChEMBL target CHEMBL4296518. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Erythrocyte
CELL-LINE
As of 2026-09-13
ChEMBL target ID
CHEMBL4296518
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Erythrocyte still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameErythrocyte
Target TypeCELL-LINE
OrganismNone
ChEMBL ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelErythrocyte
UniProt AccessionN/A

Erythrocyte

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Erythrocyte.

Review nameErythrocyte
Clinical Profile

Clinical Phase Distribution

3
Approved
Assay Mix

Activity Type Distribution

IC50282.0
EC50215.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5437832 10.26 IC50 0.055 Preclinical
CHEMBL5422826 10.26 IC50 0.055 Preclinical
CHEMBL5420542 10.26 IC50 0.055 Preclinical
CHEMBL5409080 10.26 IC50 0.055 Preclinical
CHEMBL5407096 10.26 IC50 0.055 Preclinical
CHEMBL5401736 10.26 IC50 0.055 Preclinical
CHEMBL5401652 10.26 IC50 0.055 Preclinical
CHEMBL5396997 10.26 IC50 0.055 Preclinical
CHEMBL5220104 7.77 IC50 17.0 Preclinical
CHEMBL5219562 7.77 IC50 17.0 Preclinical
Distribution

pChEMBL Value Distribution

9
5.0
14
5.5
9
6.0
9
6.5
6
7.0
3
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

DICLOFENAC
CHEMBL139
Approved 1988
Properties Compare Identifier
AMPICILLIN
CHEMBL174
Approved 1965
Properties Compare Identifier
Assay Landscape

Assay Landscape

1,042
Total Assays
56
Tested Compounds
3
Assay Types
ADME — 415 assays, 19 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 415 19 5.1
Toxicity — 376 assays, 56 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 376 56 6.6
Functional — 251 assays, 50 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 251 50 5.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine