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Target Snapshot

CHEMBL4296544 Target Snapshot

Uterus · TISSUE · Rattus norvegicus

33Compounds
8Assays
0Approved Drugs
28.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Uterus as ChEMBL target CHEMBL4296544. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Uterus
TISSUE · Rattus norvegicus
As of 2026-09-14
ChEMBL target ID
CHEMBL4296544
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Uterus still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelUterus
UniProt AccessionN/A

Uterus

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Uterus.

Review nameUterus
OrganismRattus norvegicus
Clinical Profile

Clinical Phase Distribution

3
Phase III
Assay Mix

Activity Type Distribution

IC5028.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4214302 8.08 IC50 8.24 Preclinical
CHEMBL4205031 7.88 IC50 13.3 Preclinical
CHEMBL4211183 7.72 IC50 18.9 Preclinical
CHEMBL4213799 7.62 IC50 24.2 Preclinical
CHEMBL4209904 7.49 IC50 32.2 Preclinical
CHEMBL4218725 7.43 IC50 37.1 Preclinical
CHEMBL4206817 7.38 IC50 41.8 Preclinical
CHEMBL4214710 7.07 IC50 84.5 Preclinical
CHEMBL4207820 7.04 IC50 90.2 Preclinical
CHEMBL4218558 7.01 IC50 98.1 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
5
5.5
8
6.0
5
6.5
6
7.0
3
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

8
Total Assays
28
Tested Compounds
1
Assay Types
Functional — 8 assays, 28 compounds
BAO Format Assays Compounds Avg pChEMBL
tissue-based format 6 28 6.7
organism-based format 2 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine