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Target Snapshot

CHEMBL4303840 Target Snapshot

Vero C1008 · CELL-LINE · Chlorocebus sabaeus

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1,454Compounds
191Assays
0Approved Drugs
127.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Vero C1008 as ChEMBL target CHEMBL4303840. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Vero C1008
CELL-LINE · Chlorocebus sabaeus
As of 2026-09-14
ChEMBL target ID
CHEMBL4303840
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Vero C1008 still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameVero C1008
Target TypeCELL-LINE
OrganismChlorocebus sabaeus
ChEMBL ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelVero C1008
UniProt AccessionN/A

Vero C1008

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Vero C1008.

Review nameVero C1008
OrganismChlorocebus sabaeus
Assay Mix

Activity Type Distribution

IC50127.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5421019 8.29 IC50 5.11 Preclinical
CHEMBL5170414 5.39 IC50 4100.0 Preclinical
CHEMBL5190629 5.25 IC50 5600.0 Preclinical
CHEMBL4874417 5.1 IC50 7940.0 Preclinical
CHEMBL4159207 5.0 IC50 10000.0 Preclinical
CHEMBL4169467 5.0 IC50 10000.0 Preclinical
CHEMBL5208190 4.91 IC50 12400.0 Preclinical
CHEMBL4167120 4.85 IC50 14000.0 Preclinical
CHEMBL4859986 4.85 IC50 14130.0 Preclinical
CHEMBL4877865 4.85 IC50 14130.0 Preclinical
Distribution

pChEMBL Value Distribution

5
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

192
Total Assays
58
Tested Compounds
3
Assay Types
Toxicity — 138 assays, 12 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 138 12 5.2
ADME — 52 assays, 58 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 52 58 4.5
Functional — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine