Cysteinyl leukotriene receptor 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9NS75. Use UniProt Q9NS75 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9NS75 as the stable identity anchor, then attach disease evidence before program review.
Cysteinyl leukotriene receptor 2
Review this target as Cysteinyl leukotriene receptor 2, mapped to UniProt Q9NS75. Sequence length is 346 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cysteinyl leukotriene receptor 2 as ChEMBL target CHEMBL4330, mapped to UniProt Q9NS75. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cysteinyl leukotriene receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9NS75 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cysteinyl leukotriene receptor 2 |
| UniProt Accession | Q9NS75 |
| Component Type | Protein |
| Sequence Length | 346 aa |
Cysteinyl leukotriene receptor 2
Review this target as Cysteinyl leukotriene receptor 2, mapped to UniProt Q9NS75. Sequence length is 346 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3403187 | 9.51 | IC50 | 0.31 | Preclinical |
| CHEMBL3401689 | 9.31 | IC50 | 0.49 | Preclinical |
| CHEMBL3342959 | 9.21 | IC50 | 0.62 | Preclinical |
| CHEMBL3342964 | 9.06 | IC50 | 0.87 | Preclinical |
| CHEMBL3597618 | 9.06 | IC50 | 0.88 | Preclinical |
| CHEMBL3597616 | 9.05 | IC50 | 0.89 | Preclinical |
| CHEMBL3597530 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL3597532 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL3597525 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL3597533 | 8.66 | IC50 | 2.2 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 82 | 7.1 |
| assay format | 2 | 3 | 7.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 1 | 5.3 |
| cell-based format | 2 | 2 | 5.3 |