Prostaglandin-H2 D-isomerase · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt O09114. Use UniProt O09114 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O09114 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin-H2 D-isomerase
Review this target as Prostaglandin-H2 D-isomerase, mapped to UniProt O09114. Sequence length is 189 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin-H2 D-isomerase as ChEMBL target CHEMBL4334, mapped to UniProt O09114. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin-H2 D-isomerase |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | O09114 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin-H2 D-isomerase |
| UniProt Accession | O09114 |
| Component Type | Protein |
| Sequence Length | 189 aa |
Prostaglandin-H2 D-isomerase
Review this target as Prostaglandin-H2 D-isomerase, mapped to UniProt O09114. Sequence length is 189 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL13078 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL274833 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL13288 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL2092862 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL13376 | 6.7 | IC50 | 200.0 | Approved |
| CHEMBL469 | 6.64 | IC50 | 230.0 | Approved |
| CHEMBL13215 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL273700 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL6 | 6.3 | IC50 | 500.0 | Approved |
| CHEMBL12566 | 6.24 | IC50 | 570.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| microsome format | 6 | 27 | 5.8 |
| single protein format | 1 | 2 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| microsome format | 1 | 0 | — |