Prostaglandin E2 receptor EP3 subtype · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P30557. Use UniProt P30557 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30557 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin E2 receptor EP3 subtype
Review this target as Prostaglandin E2 receptor EP3 subtype, mapped to UniProt P30557. Sequence length is 365 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin E2 receptor EP3 subtype as ChEMBL target CHEMBL4336, mapped to UniProt P30557. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin E2 receptor EP3 subtype |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P30557 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin E2 receptor EP3 subtype |
| UniProt Accession | P30557 |
| Component Type | Protein |
| Sequence Length | 365 aa |
Prostaglandin E2 receptor EP3 subtype
Review this target as Prostaglandin E2 receptor EP3 subtype, mapped to UniProt P30557. Sequence length is 365 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1091742 | 10.19 | Ki | 0.065 | Preclinical |
| CHEMBL1094161 | 10.17 | Ki | 0.068 | Preclinical |
| CHEMBL1091741 | 10.07 | Ki | 0.086 | Preclinical |
| CHEMBL597348 | 10.05 | Ki | 0.09 | Preclinical |
| CHEMBL597375 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL603881 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL599203 | 9.96 | Ki | 0.11 | Preclinical |
| CHEMBL1090937 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL599812 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL603497 | 9.89 | Ki | 0.13 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 16 | 216 | 7.8 |
| single protein format | 7 | 14 | 7.4 |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 124 | 7.4 |