N-acylethanolamine-hydrolyzing acid amidase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q02083. Use UniProt Q02083 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q02083 as the stable identity anchor, then attach disease evidence before program review.
N-acylethanolamine-hydrolyzing acid amidase
Review this target as N-acylethanolamine-hydrolyzing acid amidase, mapped to UniProt Q02083. Sequence length is 359 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats N-acylethanolamine-hydrolyzing acid amidase as ChEMBL target CHEMBL4349, mapped to UniProt Q02083. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | N-acylethanolamine-hydrolyzing acid amidase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q02083 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | N-acylethanolamine-hydrolyzing acid amidase |
| UniProt Accession | Q02083 |
| Component Type | Protein |
| Sequence Length | 359 aa |
N-acylethanolamine-hydrolyzing acid amidase
Review this target as N-acylethanolamine-hydrolyzing acid amidase, mapped to UniProt Q02083. Sequence length is 359 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4633233 | 9.46 | IC50 | 0.35 | Preclinical |
| CHEMBL4640552 | 9.34 | IC50 | 0.46 | Preclinical |
| CHEMBL4642793 | 9.33 | IC50 | 0.47 | Preclinical |
| CHEMBL4635208 | 9.17 | IC50 | 0.68 | Preclinical |
| CHEMBL4640519 | 9.07 | IC50 | 0.85 | Preclinical |
| CHEMBL4644090 | 9.06 | IC50 | 0.88 | Preclinical |
| CHEMBL4633213 | 9.05 | IC50 | 0.89 | Preclinical |
| CHEMBL4649536 | 9.03 | IC50 | 0.94 | Preclinical |
| CHEMBL4637701 | 8.99 | IC50 | 1.03 | Preclinical |
| CHEMBL4646880 | 8.96 | IC50 | 1.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 37 | 131 | 6.5 |
| single protein format | 25 | 203 | 7.2 |
| assay format | 3 | 72 | 6.0 |