Use UniProt P07265 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4357 Target Snapshot
Alpha-glucosidase MAL62 · SINGLE PROTEIN · Saccharomyces cerevisiae
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As of 2026-09-14Protein identity stays anchored to UniProt P07265. Use UniProt P07265 as the stable identity anchor, then attach disease evidence before program review.
Alpha-glucosidase MAL62
Review this target as Alpha-glucosidase MAL62, mapped to UniProt P07265. Sequence length is 584 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Alpha-glucosidase MAL62 as ChEMBL target CHEMBL4357, mapped to UniProt P07265. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Alpha-glucosidase MAL62 is the right protein anchor across sources, using UniProt P07265 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Alpha-glucosidase MAL62 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae |
| UniProt | P07265 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Alpha-glucosidase MAL62 |
| UniProt Accession | P07265 |
| Component Type | Protein |
| Sequence Length | 584 aa |
Alpha-glucosidase MAL62
How to read this target
Review this target as Alpha-glucosidase MAL62, mapped to UniProt P07265. Sequence length is 584 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL80254 | 6.08 | IC50 | 840.0 | Preclinical |
| CHEMBL312653 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL387689 | 4.77 | IC50 | 17090.0 | Preclinical |
| CHEMBL1760547 | 4.33 | IC50 | 47200.0 | Preclinical |
| CHEMBL559089 | 4.32 | IC50 | 48200.0 | Preclinical |
| CHEMBL559089 | 4.19 | Ki | 64400.0 | Preclinical |
| CHEMBL1760551 | 4.18 | IC50 | 66200.0 | Preclinical |
| CHEMBL247666 | 4.11 | IC50 | 78000.0 | Preclinical |
| CHEMBL1760546 | 4.09 | IC50 | 80800.0 | Preclinical |
| CHEMBL1760547 | 4.09 | Ki | 81600.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 12 assays, 17 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 12 | 17 | 4.5 |