Photoreceptor-specific nuclear receptor · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9Y5X4. Use UniProt Q9Y5X4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Y5X4 as the stable identity anchor, then attach disease evidence before program review.
Photoreceptor-specific nuclear receptor
Review this target as Photoreceptor-specific nuclear receptor, mapped to UniProt Q9Y5X4. Sequence length is 410 aa.
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This review treats Photoreceptor-specific nuclear receptor as ChEMBL target CHEMBL4374, mapped to UniProt Q9Y5X4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Photoreceptor-specific nuclear receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9Y5X4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Photoreceptor-specific nuclear receptor |
| UniProt Accession | Q9Y5X4 |
| Component Type | Protein |
| Sequence Length | 410 aa |
Photoreceptor-specific nuclear receptor
Review this target as Photoreceptor-specific nuclear receptor, mapped to UniProt Q9Y5X4. Sequence length is 410 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL386138 | 7.46 | EC50 | 35.0 | Preclinical |
| CHEMBL1391310 | 6.86 | IC50 | 139.1 | Preclinical |
| CHEMBL1232381 | 6.83 | IC50 | 149.12 | Preclinical |
| CHEMBL213426 | 6.83 | EC50 | 147.0 | Preclinical |
| CHEMBL1602811 | 6.78 | IC50 | 167.27 | Preclinical |
| CHEMBL384623 | 6.77 | EC50 | 170.0 | Preclinical |
| CHEMBL1384281 | 6.75 | IC50 | 177.87 | Preclinical |
| CHEMBL1575389 | 6.75 | IC50 | 177.89 | Preclinical |
| CHEMBL1326814 | 6.73 | IC50 | 185.5 | Preclinical |
| CHEMBL1324779 | 6.66 | IC50 | 220.17 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 139 | 5.5 |
| cell-based format | 2 | 18 | 6.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |