Disintegrin and metalloproteinase domain-containing protein 17 · SINGLE PROTEIN · Mus musculus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q9Z0F8. Use UniProt Q9Z0F8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Z0F8 as the stable identity anchor, then attach disease evidence before program review.
Disintegrin and metalloproteinase domain-containing protein 17
Review this target as Disintegrin and metalloproteinase domain-containing protein 17, mapped to UniProt Q9Z0F8. Sequence length is 827 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Disintegrin and metalloproteinase domain-containing protein 17 as ChEMBL target CHEMBL4379, mapped to UniProt Q9Z0F8. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Disintegrin and metalloproteinase domain-containing protein 17 is the right protein anchor across sources, using UniProt Q9Z0F8 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Disintegrin and metalloproteinase domain-containing protein 17 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9Z0F8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Disintegrin and metalloproteinase domain-containing protein 17 |
| UniProt Accession | Q9Z0F8 |
| Component Type | Protein |
| Sequence Length | 827 aa |
Disintegrin and metalloproteinase domain-containing protein 17
Review this target as Disintegrin and metalloproteinase domain-containing protein 17, mapped to UniProt Q9Z0F8. Sequence length is 827 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4067381 | 8.2 | IC50 | 6.31 | Preclinical |
| CHEMBL4078142 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL4070236 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL4105634 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL4099382 | 7.8 | IC50 | 15.85 | Preclinical |
| CHEMBL4074005 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL4097420 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL4076142 | 7.72 | IC50 | 19.0 | Preclinical |
| CHEMBL4069740 | 7.7 | IC50 | 19.95 | Preclinical |
| CHEMBL4075636 | 7.7 | IC50 | 19.95 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 51 | 6.9 |