Fructose-1,6-bisphosphatase 1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P19112. Use UniProt P19112 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P19112 as the stable identity anchor, then attach disease evidence before program review.
Fructose-1,6-bisphosphatase 1
Review this target as Fructose-1,6-bisphosphatase 1, mapped to UniProt P19112. Sequence length is 363 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Fructose-1,6-bisphosphatase 1 as ChEMBL target CHEMBL4391, mapped to UniProt P19112. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Fructose-1,6-bisphosphatase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P19112 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Fructose-1,6-bisphosphatase 1 |
| UniProt Accession | P19112 |
| Component Type | Protein |
| Sequence Length | 363 aa |
Fructose-1,6-bisphosphatase 1
Review this target as Fructose-1,6-bisphosphatase 1, mapped to UniProt P19112. Sequence length is 363 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL123678 | 6.47 | IC50 | 340.0 | Preclinical |
| CHEMBL571017 | 6.46 | IC50 | 350.0 | Preclinical |
| CHEMBL570326 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL571207 | 6.35 | IC50 | 450.0 | Preclinical |
| CHEMBL571872 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL419776 | 6.28 | IC50 | 520.0 | Preclinical |
| CHEMBL570790 | 6.26 | IC50 | 550.0 | Preclinical |
| CHEMBL572055 | 6.19 | IC50 | 650.0 | Preclinical |
| CHEMBL126456 | 6.1 | IC50 | 790.0 | Preclinical |
| CHEMBL3218222 | 6.1 | IC50 | 800.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 13 | 69 | 5.5 |
| cell-based format | 2 | 1 | — |
| single protein format | 1 | 1 | 5.0 |