Beta-3 adrenergic receptor · SINGLE PROTEIN · Canis lupus familiaris
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As of 2026-09-14Protein identity stays anchored to UniProt O02662. Use UniProt O02662 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O02662 as the stable identity anchor, then attach disease evidence before program review.
Beta-3 adrenergic receptor
Review this target as Beta-3 adrenergic receptor, mapped to UniProt O02662. Sequence length is 405 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-3 adrenergic receptor as ChEMBL target CHEMBL4400, mapped to UniProt O02662. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Beta-3 adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Canis lupus familiaris |
| UniProt | O02662 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-3 adrenergic receptor |
| UniProt Accession | O02662 |
| Component Type | Protein |
| Sequence Length | 405 aa |
Beta-3 adrenergic receptor
Review this target as Beta-3 adrenergic receptor, mapped to UniProt O02662. Sequence length is 405 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3128194 | 9.72 | EC50 | 0.19 | Preclinical |
| CHEMBL486051 | 9.72 | EC50 | 0.19 | Preclinical |
| CHEMBL507506 | 9.29 | EC50 | 0.51 | Preclinical |
| CHEMBL469395 | 9.2 | EC50 | 0.631 | Preclinical |
| CHEMBL470856 | 9.17 | EC50 | 0.68 | Preclinical |
| CHEMBL469821 | 9.06 | EC50 | 0.88 | Preclinical |
| CHEMBL272584 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL452134 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL515397 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL551272 | 9.0 | EC50 | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 10 | 36 | 8.5 |
| assay format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |