Retinoic acid receptor RXR-gamma · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P28705. Use UniProt P28705 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P28705 as the stable identity anchor, then attach disease evidence before program review.
Retinoic acid receptor RXR-gamma
Review this target as Retinoic acid receptor RXR-gamma, mapped to UniProt P28705. Sequence length is 463 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Retinoic acid receptor RXR-gamma as ChEMBL target CHEMBL4402, mapped to UniProt P28705. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Retinoic acid receptor RXR-gamma |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P28705 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinoic acid receptor RXR-gamma |
| UniProt Accession | P28705 |
| Component Type | Protein |
| Sequence Length | 463 aa |
Retinoic acid receptor RXR-gamma
Review this target as Retinoic acid receptor RXR-gamma, mapped to UniProt P28705. Sequence length is 463 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL310047 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL288436 | 8.52 | Kd | 3.0 | Preclinical |
| CHEMBL288436 | 8.4 | EC50 | 4.0 | Preclinical |
| CHEMBL705 | 8.4 | Kd | 4.0 | Approved |
| CHEMBL109117 | 8.3 | EC50 | 5.0 | Preclinical |
| CHEMBL80236 | 8.3 | Ki | 5.0 | Preclinical |
| CHEMBL310047 | 8.3 | Ki | 5.0 | Preclinical |
| CHEMBL38 | 8.22 | EC50 | 6.0 | Approved |
| CHEMBL80236 | 8.22 | EC50 | 6.0 | Preclinical |
| CHEMBL312395 | 8.15 | Ki | 7.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 35 | 7.0 |
| single protein format | 7 | 46 | 6.9 |
| assay format | 1 | 14 | 6.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 4 | 7.3 |